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IDEAL
2004
Springer
14 years 22 days ago
Combining Local and Global Models to Capture Fast and Slow Dynamics in Time Series Data
Many time series exhibit dynamics over vastly different time scales. The standard way to capture this behavior is to assume that the slow dynamics are a “trend”, to de-trend t...
Michael Small
HPDC
2010
IEEE
13 years 8 months ago
Modeling sequence and function similarity between proteins for protein functional annotation
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Roger Higdon, Brenton Louie, Eugene Kolker
JCB
2007
198views more  JCB 2007»
13 years 7 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
BMCBI
2008
115views more  BMCBI 2008»
13 years 7 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
SIAMAM
2000
128views more  SIAMAM 2000»
13 years 7 months ago
Advection-Diffusion Equations for Internal State-Mediated Random Walks
Abstract. In many biological examples of biased random walks, movement statistics are determined by state dynamics that are internal to the organism or cell and that mediate respon...
Daniel Grünbaum