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ISMB
2007
13 years 10 months ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
BMCBI
2010
113views more  BMCBI 2010»
13 years 7 months ago
Unifying generative and discriminative learning principles
Background: The recognition of functional binding sites in genomic DNA remains one of the fundamental challenges of genome research. During the last decades, a plethora of differe...
Jens Keilwagen, Jan Grau, Stefan Posch, Marc Stric...
BMCBI
2006
203views more  BMCBI 2006»
13 years 7 months ago
Genome-wide prediction of transcriptional regulatory elements of human promoters using gene expression and promoter analysis dat
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
Seon-Young Kim, YongSung Kim
ISBRA
2010
Springer
13 years 6 months ago
A Consensus Tree Approach for Reconstructing Human Evolutionary History and Detecting Population Substructure
The random accumulation of variations in the human genome over time implicitly encodes a history of how human populations have arisen, dispersed, and intermixed since we emerged as...
Ming-Chi Tsai, Guy E. Blelloch, R. Ravi, Russell S...
BMCBI
2011
13 years 2 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...