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PADL
2009
Springer
14 years 8 months ago
Using Bloom Filters for Large Scale Gene Sequence Analysis in Haskell
Analysis of biological data often involves large data sets and computationally expensive algorithms. Databases of biological data continue to grow, leading to an increasing demand ...
Ketil Malde, Bryan O'Sullivan
BMCBI
2010
113views more  BMCBI 2010»
13 years 7 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
BIOINFORMATICS
2004
59views more  BIOINFORMATICS 2004»
13 years 7 months ago
Efficient selection of unique and popular oligos for large EST databases
EST databases have grown exponentially in recent years and now represent the largest collection of genetic sequences. An important application of these databases is that they conta...
Jie Zheng, Timothy J. Close, Tao Jiang, Stefano Lo...