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BMCBI
2006
13 years 8 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
BMCBI
2006
13 years 8 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
BMCBI
2006
13 years 8 months ago
2006
Background: In Eukaryotic genomes, different features including genes are not uniformly distributed. The integration of annotation information and genomic position of functional D...
BMCBI
2006
13 years 8 months ago
2006
Background: We describe Distill, a suite of servers for the prediction of protein structural features: secondary structure; relative solvent accessibility; contact density; backbo...
CONSTRAINTS
2006
13 years 8 months ago
2006
Constraint satisfaction problems (CSPs) sometimes contain both variable symmetries and value symmetries, causing adverse effects on CSP solvers based on tree search. As a remedy, s...