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2005
Springer
13 years 7 months ago
Fast Protein Superfamily Classification Using Principal Component Null Space Analysis
Abstract. The protein family classification problem, which consists of determining the family memberships of given unknown protein sequences, is very important for a biologist for ...
Leon French, Alioune Ngom, Luis Rueda
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
SVM-based prediction of caspase substrate cleavage sites
Background: Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sit...
Lawrence J. K. Wee, Tin Wee Tan, Shoba Ranganathan
BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
BMCBI
2005
120views more  BMCBI 2005»
13 years 7 months ago
pSLIP: SVM based protein subcellular localization prediction using multiple physicochemical properties
Background: Protein subcellular localization is an important determinant of protein function and hence, reliable methods for prediction of localization are needed. A number of pre...
Deepak Sarda, Gek Huey Chua, Kuo-Bin Li, Arun Kris...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...