Background: Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique fo...
Gift Nyamundanda, Lorraine Brennan, Isobel Claire ...
Normal mixture models are widely used for statistical modeling of data, including cluster analysis. However maximum likelihood estimation (MLE) for normal mixtures using the EM al...
When performing subspace modelling of data using Principal Component Analysis (PCA) it may be desirable to constrain certain directions to be more meaningful in the context of the...
Traditional techniques for statistical fMRI analysis are often based on thresholding of individual voxel values or averaging voxel values over a region of interest. In this paper w...
Background: This paper addresses key biological problems and statistical issues in the analysis of large gene expression data sets that describe systemic temporal response cascade...