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BMCBI
2008
107views more  BMCBI 2008»
13 years 6 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2004
139views more  BMCBI 2004»
13 years 6 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
CSDA
2007
151views more  CSDA 2007»
13 years 6 months ago
Robust semiparametric mixing for detecting differentially expressed genes in microarray experiments
An important goal of microarray studies is the detection of genes that show significant changes in observed expressions when two or more classes of biological samples such as tre...
Marco Alfò, Alessio Farcomeni, Luca Tardell...
BMCBI
2006
106views more  BMCBI 2006»
13 years 6 months ago
Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Henrik Bengtsson, Ola Hössjer
BMCBI
2006
126views more  BMCBI 2006»
13 years 6 months ago
OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Morgan N. Price, Adam P. Arkin, Eric J. Alm