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» Bayesian modelling of shared gene function
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CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
14 years 3 months ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision
BMCBI
2006
131views more  BMCBI 2006»
13 years 10 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...
UAI
2003
13 years 11 months ago
Learning Module Networks
Methods for learning Bayesian networks can discover dependency structure between observed variables. Although these methods are useful in many applications, they run into computat...
Eran Segal, Dana Pe'er, Aviv Regev, Daphne Koller,...
BMCBI
2008
128views more  BMCBI 2008»
13 years 10 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
13 years 7 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen