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BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
CPHYSICS
2006
127views more  CPHYSICS 2006»
13 years 7 months ago
GenAnneal: Genetically modified Simulated Annealing
A modification of the standard Simulated Annealing (SA) algorithm is presented for finding the global minimum of a continuous multidimensional, multimodal function. We report resu...
Ioannis G. Tsoulos, Isaac E. Lagaris
CPHYSICS
2006
204views more  CPHYSICS 2006»
13 years 7 months ago
Genetically controlled random search: a global optimization method for continuous multidimensional functions
A new stochastic method for locating the global minimum of a multidimensional function inside a rectangular hyperbox is presented. A sampling technique is employed that makes use ...
Ioannis G. Tsoulos, Isaac E. Lagaris
CPHYSICS
2006
182views more  CPHYSICS 2006»
13 years 7 months ago
MinFinder: Locating all the local minima of a function
A new stochastic clustering algorithm is introduced that aims to locate all the local minima of a multidimensional continuous and differentiable function inside a bounded domain. ...
Ioannis G. Tsoulos, Isaac E. Lagaris