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BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Binning sequences using very sparse labels within a metagenome
Background: In metagenomic studies, a process called binning is necessary to assign contigs that belong to multiple species to their respective phylogenetic groups. Most of the cu...
Chon-Kit Kenneth Chan, Arthur L. Hsu, Saman K. Hal...
BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
BMCBI
2008
97views more  BMCBI 2008»
13 years 7 months ago
Interrogating domain-domain interactions with parsimony based approaches
Background: The identification and characterization of interacting domain pairs is an important step towards understanding protein interactions. In the last few years, several met...
Katia S. Guimarães, Teresa M. Przytycka
BMCBI
2008
127views more  BMCBI 2008»
13 years 7 months ago
Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides
Background: Promoter region plays an important role in determining where the transcription of a particular gene should be initiated. Computational prediction of eukaryotic Pol II ...
Jian-Yi Yang, Yu Zhou, Zu-Guo Yu, Vo Anh, Li-Qian ...
BMCBI
2008
147views more  BMCBI 2008»
13 years 7 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...