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» Biclustering of Expression Data Using Simulated Annealing
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BMCBI
2006
92views more  BMCBI 2006»
13 years 8 months ago
Predicting survival outcomes using subsets of significant genes in prognostic marker studies with microarrays
Background: Genetic markers hold great promise for refining our ability to establish precise prognostic prediction for diseases. The development of comprehensive gene expression m...
Shigeyuki Matsui
BMCBI
2006
110views more  BMCBI 2006»
13 years 8 months ago
Bias in error estimation when using cross-validation for model selection
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
Sudhir Varma, Richard Simon
ICDE
2005
IEEE
139views Database» more  ICDE 2005»
14 years 10 months ago
Compressing Bitmap Indices by Data Reorganization
Many scientific applications generate massive volumes of data through observations or computer simulations, bringing up the need for effective indexing methods for efficient stora...
Ali Pinar, Tao Tao, Hakan Ferhatosmanoglu
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
13 years 10 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi
BMCBI
2011
13 years 3 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung