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BMCBI
2008
167views more  BMCBI 2008»
13 years 11 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2008
120views more  BMCBI 2008»
13 years 11 months ago
DBMLoc: a Database of proteins with multiple subcellular localizations
Background: Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein...
Song Zhang, Xuefeng Xia, Jincheng Shen, Yun Zhou, ...
BMCBI
2008
115views more  BMCBI 2008»
13 years 11 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
BMCBI
2008
188views more  BMCBI 2008»
13 years 11 months ago
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...
Nicola Zamboni, Anne Kümmel, Matthias Heinema...
BMCBI
2008
128views more  BMCBI 2008»
13 years 11 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...