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BMCBI
2006
117views more  BMCBI 2006»
13 years 11 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
BMCBI
2006
130views more  BMCBI 2006»
13 years 11 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
BMCBI
2006
139views more  BMCBI 2006»
13 years 11 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
BMCBI
2006
130views more  BMCBI 2006»
13 years 11 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
CONNECTION
2006
172views more  CONNECTION 2006»
13 years 11 months ago
Temporal sequence detection with spiking neurons: towards recognizing robot language instructions
We present an approach for recognition and clustering of spatio temporal patterns based on networks of spiking neurons with active dendrites and dynamic synapses. We introduce a n...
Christo Panchev, Stefan Wermter