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BMCBI
2006
180views more  BMCBI 2006»
13 years 8 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BIOSYSTEMS
2007
82views more  BIOSYSTEMS 2007»
13 years 8 months ago
Homeostatic plasticity improves signal propagation in continuous-time recurrent neural networks
Continuous-time recurrent neural networks (CTRNNs) are potentially an excellent substrate for the generation of adaptive behaviour in artificial autonomous agents. However, node ...
Hywel T. P. Williams, Jason Noble
IWANN
2009
Springer
14 years 2 months ago
GREAT: Gene Regulation EvAluation Tool
Our understanding of biological systems is highly dependent on the study of the mechanisms that regulate genetic expression. In this paper we present a tool to evaluate scientific ...
Catia Machado, Hugo P. Bastos, Francisco M. Couto
BMCBI
2010
83views more  BMCBI 2010»
13 years 8 months ago
Trees on networks: resolving statistical patterns of phylogenetic similarities among interacting proteins
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...
William P. Kelly, Michael P. H. Stumpf
JELIA
2004
Springer
14 years 1 months ago
Towards a Logical Analysis of Biochemical Pathways
Biochemical pathways or networks are generic representations used to model many different types of complex functional and physical interactions in biological systems. Models based ...
Patrick Doherty, Steve Kertes, Martin Magnusson, A...