Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
Stephanie Heinen, Bernhard Thielen, Dietmar Schomb...
A central problem in bioinformatics and systems biology is the selection of appropriate models in a rational and systematic way. This fundamentally combinatorial problem can be re...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Ioa...
— The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. We are investigating the possibility of de...