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» Biological pathway inference using manifold embedding
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IAT
2010
IEEE
13 years 6 months ago
A Biologically-Inspired Cognitive Agent Model Integrating Declarative Knowledge and Reinforcement Learning
Abstract--The paper proposes a biologically-inspired cognitive agent model, known as FALCON-X, based on an integration of the Adaptive Control of Thought (ACT-R) architecture and a...
Ah-Hwee Tan, Gee Wah Ng
BIOCOMP
2006
13 years 10 months ago
Computational Inference of Compound-induced Anti-inflammatory Effects Across Time in an Adjuvant-induced Arthritis Rat Model
A number of diseases, such as arthritis and cardiovascular disorders impacting the lives of many people have strong inflammatory components. To elucidate the antiinflammatory mecha...
Jing Yu, Gabriel Helmlinger, Muriel Saulnier, Anna...
DILS
2005
Springer
14 years 2 months ago
Setup and Annotation of Metabolomic Experiments by Integrating Biological and Mass Spectrometric Metadata
Unbiased metabolomic surveys are used for physiological, clinical and genomic studies to infer genotype-phenotype relationships. Long term reusability of metabolomic data needs bot...
Oliver Fiehn, Gert Wohlgemuth, Martin Scholz
BIOCOMP
2006
13 years 10 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
BMCBI
2005
169views more  BMCBI 2005»
13 years 8 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader