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BMCBI
2006
141views more  BMCBI 2006»
13 years 7 months ago
Visual setup of logical models of signaling and regulatory networks with ProMoT
Background: The analysis of biochemical networks using a logical (Boolean) description is an important approach in Systems Biology. Recently, new methods have been proposed to ana...
Julio Saez-Rodriguez, Sebastian Mirschel, Rebecca ...
ENTCS
2002
125views more  ENTCS 2002»
13 years 7 months ago
Pathway Logic: Executable Models of Biological Networks
In this paper we describe the use of the rewriting logic based Maude tool to model and analyze mammalian signaling pathways. We discuss the representation of the underlying biolog...
Steven Eker, Merrill Knapp, Keith Laderoute, Patri...
CMPB
2010
171views more  CMPB 2010»
13 years 2 months ago
Metabolica: A statistical research tool for analyzing metabolic networks
Steady state flux balance analysis (FBA) for cellular metabolism is used, e.g., to seek information on the activity of the different pathways under equilibrium conditions, or as a...
Jenni Heino, Daniela Calvetti, Erkki Somersalo
RECOMB
2000
Springer
13 years 11 months ago
Using Bayesian networks to analyze expression data
DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a "snapshot" of transcription levels within the c...
Nir Friedman, Michal Linial, Iftach Nachman, Dana ...
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...