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» Building Large Knowledge Bases in Molecular Biology
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CSB
2005
IEEE
180views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Functional Modularity in a Large-Scale Mammalian Molecular Interaction Network
The Ingenuity™ Pathways Knowledge Base (IPKB) contains over one million findings manually curated from the scientific literature. Highly-structured content from the IPKB forms...
Andreas Kramer, Daniel R. Richards, James O. Bowlb...
WWW
2006
ACM
14 years 8 months ago
Knowledge modeling and its application in life sciences: a tale of two ontologies
High throughput glycoproteomics, similar to genomics and proteomics, involves extremely large volumes of distributed, heterogeneous data as a basis for identification and quantifi...
Satya Sanket Sahoo, Christopher Thomas, Amit P. Sh...
BMCBI
2006
174views more  BMCBI 2006»
13 years 7 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
SIAMSC
2008
182views more  SIAMSC 2008»
13 years 7 months ago
A Distributed SDP Approach for Large-Scale Noisy Anchor-Free Graph Realization with Applications to Molecular Conformation
We propose a distributed algorithm for solving Euclidean metric realization problems arising from large 3D graphs, using only noisy distance information, and without any prior kno...
Pratik Biswas, Kim-Chuan Toh, Yinyu Ye
BMCBI
2006
203views more  BMCBI 2006»
13 years 7 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...