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» Building Large Knowledge Bases in Molecular Biology
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BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2011
12 years 11 months ago
To aggregate or not to aggregate high-dimensional classifiers
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
KDD
2009
ACM
189views Data Mining» more  KDD 2009»
14 years 2 months ago
CoCo: coding cost for parameter-free outlier detection
How can we automatically spot all outstanding observations in a data set? This question arises in a large variety of applications, e.g. in economy, biology and medicine. Existing ...
Christian Böhm, Katrin Haegler, Nikola S. M&u...
CIKM
2004
Springer
14 years 24 days ago
Hierarchical document categorization with support vector machines
Automatically categorizing documents into pre-defined topic hierarchies or taxonomies is a crucial step in knowledge and content management. Standard machine learning techniques ...
Lijuan Cai, Thomas Hofmann
BMCBI
2010
170views more  BMCBI 2010»
13 years 7 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...