Whether designing a new system or modifying an existing one, engineers want to take the guesswork out of finding the best possible solution. While there are many analysis methods ...
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Background: The use of ontologies to control vocabulary and structure annotation has added value to genomescale data, and contributed to the capture and re-use of knowledge across...
Melissa J. Davis, Muhammad Shoaib B. Sehgal, Mark ...
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...