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BMCBI
2008
13 years 7 months ago
2008
Background: Correctly merged data sets that have been independently genotyped can increase statistical power in linkage and association studies. However, alleles from microsatelli...
BMCBI
2008
13 years 7 months ago
2008
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
BMCBI
2006
13 years 7 months ago
2006
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
BMCBI
2006
13 years 7 months ago
2006
Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
BMCBI
2006
13 years 7 months ago
2006
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...