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CIKM
2005
Springer
14 years 1 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
CBMS
2008
IEEE
14 years 2 months ago
A New Path Length Measure Based on GO for Gene Similarity with Evaluation using SGD Pathways
We propose a new method for measuring the semantic similarity of genes based on path length between their annotation terms in the Gene Ontology. Our method applies an exponential ...
Anurag Nagar, Hisham Al-Mubaid
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
SEMCO
2007
IEEE
14 years 1 months ago
Evolutionary Conceptual Clustering of Semantically Annotated Resources
A clustering method is presented which can be applied to knowledge bases storing semantically annotated resources. The method can be used to discover groupings of structured objec...
Nicola Fanizzi, Claudia d'Amato, Floriana Esposito
BMCBI
2008
148views more  BMCBI 2008»
13 years 7 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan