Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
We propose a new method for measuring the semantic similarity of genes based on path length between their annotation terms in the Gene Ontology. Our method applies an exponential ...
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
A clustering method is presented which can be applied to knowledge bases storing semantically annotated resources. The method can be used to discover groupings of structured objec...
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...