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» COPASI - a COmplex PAthway SImulator
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BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
MBEC
2011
117views more  MBEC 2011»
12 years 10 months ago
Face activated neurodynamic cortical networks
Previous neuroimaging studies have shown that complex visual stimuli, such as faces, activate multiple brain regions, yet little is known on the dynamics and complexity of the acti...
Ana Susac, Risto J. Ilmoniemi, Douglas Ranken, Sel...
APLAS
2007
ACM
13 years 11 months ago
Scalable Simulation of Cellular Signaling Networks
Abstract. Given the combinatorial nature of cellular signalling pathways, where biological agents can bind and modify each other in a large number of ways, concurrent or agent-base...
Vincent Danos, Jérôme Feret, Walter F...
CMSB
2008
Springer
13 years 9 months ago
Automatic Complexity Analysis and Model Reduction of Nonlinear Biochemical Systems
Kinetic models for biochemical systems often comprise a large amount of coupled differential equations with species concentrations varying on different time scales. In this paper w...
Dirk Lebiedz, Dominik Skanda, Marc Fein
BMCBI
2004
323views more  BMCBI 2004»
13 years 7 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...