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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 8 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2011
13 years 10 days ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
BMCBI
2005
62views more  BMCBI 2005»
13 years 8 months ago
Differences in codon bias cannot explain differences in translational power among microbes
Background: Translational power is the cellular rate of protein synthesis normalized to the biomass invested in translational machinery. Published data suggest a previously unreco...
Les Dethlefsen, Thomas M. Schmidt
BMCBI
2005
102views more  BMCBI 2005»
13 years 8 months ago
BioCreAtIvE Task1A: entity identification with a stochastic tagger
Background: Our approach to Task 1A was inspired by Tanabe and Wilbur's ABGene system [1,2]. Like Tanabe and Wilbur, we approached the problem as one of part-of-speech taggin...
Shuhei Kinoshita, K. Bretonnel Cohen, Philip V. Og...
BMCBI
2005
84views more  BMCBI 2005»
13 years 8 months ago
Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
Youfang Cao, Lianjie Wang, Kexue Xu, Chunhai Kou, ...