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» Can we Find Molecular Signatures from Gene Expression Data
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ACSC
2005
IEEE
14 years 2 months ago
Integer Programming Models and Algorithms for Molecular Classification of Cancer from Microarray Data
Novel, high-throughput technologies are challenging the core of algorithmic methods available in Computer Science. Microarray technologies give Life Sciences researchers the oppor...
Regina Berretta, Alexandre Mendes, Pablo Moscato
BMCBI
2006
153views more  BMCBI 2006»
13 years 8 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2008
160views more  BMCBI 2008»
13 years 8 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
BMCBI
2010
84views more  BMCBI 2010»
13 years 8 months ago
Testing the additional predictive value of high-dimensional molecular data
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
Anne-Laure Boulesteix, Torsten Hothorn
DIS
2004
Springer
14 years 2 months ago
A Methodology for Biologically Relevant Pattern Discovery from Gene Expression Data
Abstract. One of the most exciting scientific challenges in functional genomics concerns the discovery of biologically relevant patterns from gene expression data. For instance, i...
Ruggero G. Pensa, Jérémy Besson, Jea...