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» Can we Find Molecular Signatures from Gene Expression Data
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JBI
2004
171views Bioinformatics» more  JBI 2004»
13 years 10 months ago
Consensus Clustering and Functional Interpretation of Gene Expression Data
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters. Obtaining a consensus s...
Paul Kellam, Stephen Swift, Allan Tucker, Veronica...
BMCBI
2010
97views more  BMCBI 2010»
13 years 6 months ago
Preprocessing of gene expression data by optimally robust estimators
Background: The preprocessing of gene expression data obtained from several platforms routinely includes the aggregation of multiple raw signal intensities to one expression value...
Matthias Kohl, Hans-Peter Deigner
RECOMB
2002
Springer
14 years 9 months ago
From promoter sequence to expression: a probabilistic framework
We present a probabilistic framework that models the process by which transcriptional binding explains the mRNA expression of different genes. Our joint probabilistic model unifie...
Eran Segal, Yoseph Barash, Itamar Simon, Nir Fried...
BMCBI
2006
99views more  BMCBI 2006»
13 years 8 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
New components of the Dictyostelium PKA pathway revealed by Bayesian analysis of expression data
Background: Identifying candidate genes in genetic networks is important for understanding regulation and biological function. Large gene expression datasets contain relevant info...
Anup Parikh, Eryong Huang, Christopher Dinh, Blaz ...