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» Can we Find Molecular Signatures from Gene Expression Data
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BMCBI
2008
130views more  BMCBI 2008»
13 years 8 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2010
144views more  BMCBI 2010»
13 years 8 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 8 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
JCB
2000
137views more  JCB 2000»
13 years 8 months ago
NOTUNG: A Program for Dating Gene Duplications and Optimizing Gene Family Trees
Large scale gene duplication is a major force driving the evolution of genetic functional innovation. Whole genome duplications are widely believed to have played an important rol...
Kevin Chen, Dannie Durand, Martin Farach-Colton
BMCBI
2005
127views more  BMCBI 2005»
13 years 8 months ago
Dynamic modeling of cis-regulatory circuits and gene expression prediction via cross-gene identification
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...