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» Can we Find Molecular Signatures from Gene Expression Data
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BMCBI
2010
126views more  BMCBI 2010»
13 years 9 months ago
GeneBrowser 2: an application to explore and identify common biological traits in a set of genes
Background: The development of high-throughput laboratory techniques created a demand for computer-assisted result analysis tools. Many of these techniques return lists of genes w...
Joel Arrais, João Fernandes, João Pe...
BMCBI
2005
133views more  BMCBI 2005»
13 years 8 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
BMCBI
2006
98views more  BMCBI 2006»
13 years 8 months ago
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Donglin Liu, Joel H. Graber
BMCBI
2006
151views more  BMCBI 2006»
13 years 8 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2004
87views more  BMCBI 2004»
13 years 8 months ago
prot4EST: Translating Expressed Sequence Tags from neglected genomes
Background: The genomes of an increasing number of species are being investigated through generation of expressed sequence tags (ESTs). However, ESTs are prone to sequencing error...
James Wasmuth, Mark L. Blaxter