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JCC
2008
88views more  JCC 2008»
13 years 7 months ago
A self-organizing algorithm for molecular alignment and pharmacophore development
Abstract: We present a method for simultaneous three-dimensional (3D) structure generation and pharmacophorebased alignment using a self-organizing algorithm called Stochastic Prox...
Deepak Bandyopadhyay, Dimitris K. Agrafiotis
ML
2008
ACM
101views Machine Learning» more  ML 2008»
13 years 7 months ago
On reoptimizing multi-class classifiers
Significant changes in the instance distribution or associated cost function of a learning problem require one to reoptimize a previously-learned classifier to work under new cond...
Chris Bourke, Kun Deng, Stephen D. Scott, Robert E...
TCS
2008
13 years 7 months ago
Algorithms for computing variants of the longest common subsequence problem
The longest common subsequence(LCS) problem is one of the classical and wellstudied problems in computer science. The computation of the LCS is a frequent task in DNA sequence ana...
Costas S. Iliopoulos, M. Sohel Rahman
BMCBI
2005
130views more  BMCBI 2005»
13 years 7 months ago
Squid - a simple bioinformatics grid
Background: BLAST is a widely used genetic research tool for analysis of similarity between nucleotide and protein sequences. This paper presents a software application entitled &...
Paulo C. Carvalho, Rafael V. Glória, Antoni...
BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe