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» Case study in modeling and simulation validation methodology
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153
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BMCBI
2010
165views more  BMCBI 2010»
15 years 3 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
144
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BMCBI
2006
99views more  BMCBI 2006»
15 years 3 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
115
Voted
BMCBI
2005
93views more  BMCBI 2005»
15 years 3 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
174
Voted
BMCBI
2005
156views more  BMCBI 2005»
15 years 3 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer
153
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SIAMAM
2000
100views more  SIAMAM 2000»
15 years 3 months ago
Phase Transition Near a Liquid-Gas Coexistence Equilibrium
Effects of small perturbations from a liquid-gas coexistence equilibrium (the Maxwell states) is studied for an isothermal (or isentropic) gas-liquid phase transition in a sealed o...
Xiao-Ping Wang, Xinfu Chen