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BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
BMCBI
2008
155views more  BMCBI 2008»
13 years 8 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2010
142views more  BMCBI 2010»
13 years 8 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
BMCBI
2008
171views more  BMCBI 2008»
13 years 8 months ago
A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more
Background: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables ...
Harri T. Kiiveri
BMCBI
2008
101views more  BMCBI 2008»
13 years 8 months ago
Term-tissue specific models for prediction of gene ontology biological processes using transcriptional profiles of aging in dros
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
Wensheng Zhang, Sige Zou, Jiuzhou Song