Background: Serial Analysis of Gene Expression (SAGE) is a functional genomic technique that quantitatively analyzes the cellular transcriptome. The analysis of SAGE libraries rel...
In this paper we survey work being conducted at Imperial College on the use of machine learning to build Systems Biology models of the effects of toxins on biochemical pathways. Se...
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
There has been considerable recent interest in the use of haplotype structure to aid in the design and analysis of case-control association studies searching for genetic predictors...
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...