Our goal is proposing an unbiased framework for gene expression analysis based on variable selection combined with a significance assessment step. We start by discussing the need ...
Annalisa Barla, Sofia Mosci, Lorenzo Rosasco, Ales...
Abstract. Our ability to simultaneously measure the expression levels of thousands of genes in biological samples is providing important new opportunities for improving the diagnos...
David M. Reif, Bill C. White, Nancy Olsen, Thomas ...
Background: Tiling array data is hard to interpret due to noise. The wavelet transformation is a widely used technique in signal processing for elucidating the true signal from no...
Alexander Karpikov, Joel S. Rozowsky, Mark Gerstei...
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...