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ALMOB
2006
155views more  ALMOB 2006»
13 years 6 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2006
130views more  BMCBI 2006»
13 years 6 months ago
CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
Kevin A. Greer, Matthew R. McReynolds, Heddwen L. ...
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
13 years 6 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
BMCBI
2006
97views more  BMCBI 2006»
13 years 6 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
INTEGRATOR: interactive graphical search of large protein interactomes over the Web
Background: The rapid growth of protein interactome data has elevated the necessity and importance of network analysis tools. However, unlike pure text data, network search spaces...
Aaron N. Chang, Jason McDermott, Zachary Frazier, ...