The advent of the Semantic Web necessitates paradigm shifts away from centralized client/server architectures towards decentralization and peer-to-peer computation, making the exi...
Ernesto Diaz-Aviles, Lars Schmidt-Thieme, Cai-Nico...
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...
Background: Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the Nomenclat...
Abstract-- Overlay networks are application layer systems which facilitate users in performing distributed functions such as searches over the contents of other users. An important...