4870 search results - page 933 / 974 » Challenges of component-based development |
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BMCBI
2006
15 years 2 months ago
2006
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
120
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BMCBI
2006
15 years 2 months ago
2006
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
135
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BMCBI
2006
15 years 2 months ago
2006
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
136
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BMCBI
2006
15 years 2 months ago
2006
Background: Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretica...
167
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BMCBI
2006
15 years 2 months ago
2006
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...