524 search results - page 24 / 105 » Challenges of sequencing human genomes |
BMCBI
2006
13 years 9 months ago
2006
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
BMCBI
2011
13 years 13 days ago
2011
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
BMCBI
2006
13 years 9 months ago
2006
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
BMCBI
2010
13 years 9 months ago
2010
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
BMCBI
2006
13 years 9 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...