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» Challenges of sequencing human genomes
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PADL
2009
Springer
14 years 9 months ago
Using Bloom Filters for Large Scale Gene Sequence Analysis in Haskell
Analysis of biological data often involves large data sets and computationally expensive algorithms. Databases of biological data continue to grow, leading to an increasing demand ...
Ketil Malde, Bryan O'Sullivan
BMCBI
2004
206views more  BMCBI 2004»
13 years 8 months ago
Combining gene expression data from different generations of oligonucleotide arrays
Background: One of the important challenges in microarray analysis is to take full advantage of previously accumulated data, both from one's own laboratory and from public re...
Kyu Baek Hwang, Sek Won Kong, Steven A. Greenberg,...
BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
BIB
2008
113views more  BIB 2008»
13 years 9 months ago
Identification of replication origins in prokaryotic genomes
The availability of hundreds of complete bacterial genomes has created new challenges and simultaneously opportunities for bioinformatics. In the area of statistical analysis of g...
Natalia V. Sernova, Mikhail S. Gelfand
SPIRE
2010
Springer
13 years 6 months ago
Identifying SNPs without a Reference Genome by Comparing Raw Reads
Next generation sequencing (NGS) technologies are being applied to many fields of biology, notably to survey the polymorphism across individuals of a species. However, while single...
Pierre Peterlongo, Nicolas Schnel, Nadia Pisanti, ...