524 search results - page 4 / 105 » Challenges of sequencing human genomes |
JCB
2007
13 years 8 months ago
2007
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
BMCBI
2006
13 years 8 months ago
2006
Background: Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of thes...
CSB
2002
IEEE
14 years 1 months ago
2002
IEEE
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
IPPS
2010
IEEE
13 years 6 months ago
2010
IEEE
Millions of DNA sequences (reads) are generated by Next Generation Sequencing machines everyday. There is a need for high performance algorithms to map these sequences to the refer...
HICSS
2003
IEEE
14 years 2 months ago
2003
IEEE
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...