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» Challenges of sequencing human genomes
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BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
TCBB
2008
93views more  TCBB 2008»
13 years 7 months ago
2SNP: Scalable Phasing Method for Trios and Unrelated Individuals
Emerging microarray technologies allow affordable typing of very long genome sequences. A key challenge in analyzing of such huge amount of data is scalable and accurate computatio...
Dumitru Brinza, Alexander Zelikovsky
BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2008
214views more  BMCBI 2008»
13 years 6 months ago
Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
Jukka Corander, Pekka Marttinen, Jukka Siré...
EUROSYS
2006
ACM
14 years 4 months ago
Automated known problem diagnosis with event traces
Computer problem diagnosis remains a serious challenge to users and support professionals. Traditional troubleshooting methods relying heavily on human intervention make the proce...
Chun Yuan, Ni Lao, Ji-Rong Wen, Jiwei Li, Zheng Zh...