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» Challenges of sequencing human genomes
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PAMI
2011
13 years 2 months ago
Learning a Family of Detectors via Multiplicative Kernels
—Object detection is challenging when the object class exhibits large within-class variations. In this work, we show that foreground-background classification (detection) and wit...
Quan Yuan, Ashwin Thangali, Vitaly Ablavsky, Stan ...
BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
BMCBI
2010
176views more  BMCBI 2010»
13 years 7 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
BMCBI
2006
161views more  BMCBI 2006»
13 years 7 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang