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BMCBI
2008
178views more  BMCBI 2008»
13 years 9 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2006
146views more  BMCBI 2006»
13 years 9 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
BMCBI
2005
117views more  BMCBI 2005»
13 years 9 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
VLSISP
2010
254views more  VLSISP 2010»
13 years 7 months ago
Manifold Based Local Classifiers: Linear and Nonlinear Approaches
Abstract In case of insufficient data samples in highdimensional classification problems, sparse scatters of samples tend to have many ‘holes’—regions that have few or no nea...
Hakan Cevikalp, Diane Larlus, Marian Neamtu, Bill ...
BMCBI
2010
227views more  BMCBI 2010»
13 years 9 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman