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» Class discovery in gene expression data
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EVOW
2008
Springer
13 years 9 months ago
Learning Gaussian Graphical Models of Gene Networks with False Discovery Rate Control
In many cases what matters is not whether a false discovery is made or not but the expected proportion of false discoveries among all the discoveries made, i.e. the so-called false...
Jose M. Peña
KDD
2004
ACM
142views Data Mining» more  KDD 2004»
14 years 8 months ago
Meta-classification of Multi-type Cancer Gene Expression Data
Massive publicly available gene expression data consisting of different experimental conditions and microarray platforms introduce new challenges in data mining when integrating m...
Benny Y. M. Fung, Vincent T. Y. Ng
JMLR
2010
125views more  JMLR 2010»
13 years 2 months ago
On utility of gene set signatures in gene expression-based cancer class prediction
Machine learning methods that can use additional knowledge in their inference process are central to the development of integrative bioinformatics. Inclusion of background knowled...
Minca Mramor, Marko Toplak, Gregor Leban, Tomaz Cu...
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate