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» Classification by Discriminative Regularization
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BMCBI
2010
129views more  BMCBI 2010»
13 years 8 months ago
Automatic prediction of catalytic residues by modeling residue structural neighborhood
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
Elisa Cilia, Andrea Passerini
BMCBI
2010
134views more  BMCBI 2010»
13 years 8 months ago
Semi-automated screening of biomedical citations for systematic reviews
Background: Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and crit...
Byron C. Wallace, Thomas A. Trikalinos, Joseph Lau...
BMCBI
2010
165views more  BMCBI 2010»
13 years 8 months ago
Multivariate meta-analysis of proteomics data from human prostate and colon tumours
Background: There is a vast need to find clinically applicable protein biomarkers as support in cancer diagnosis and tumour classification. In proteomics research, a number of met...
Lina Hultin Rosenberg, Bo Franzén, Gert Aue...
BMCBI
2008
132views more  BMCBI 2008»
13 years 8 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2008
162views more  BMCBI 2008»
13 years 8 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...