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BMCBI
2008
121views more  BMCBI 2008»
13 years 11 months ago
ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
BMCBI
2005
130views more  BMCBI 2005»
13 years 11 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
BIBE
2007
IEEE
127views Bioinformatics» more  BIBE 2007»
14 years 5 months ago
A Heuristic for Phylogenetic Reconstruction Using Transposition
Abstract—Because of the advent of high-throughput sequencing and the consequent reduction in cost of sequencing, many organisms have been completely sequenced and most of their g...
Feng Yue, Meng Zhang, Jijun Tang
BMCBI
2006
75views more  BMCBI 2006»
13 years 11 months ago
Improving the specificity of high-throughput ortholog prediction
Background: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative g...
Debra L. Fulton, Yvonne Y. Li, Matthew R. Laird, B...
BMCBI
2006
102views more  BMCBI 2006»
13 years 11 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan