Gene duplication and divergence is a major evolutionary force. Despite the growing number of fully sequenced genomes, methods for investigating these events on a genome-wide scale...
Ilan Wapinski, Avi Pfeffer, Nir Friedman, Aviv Reg...
As the logical next step after sequencing the mouse genome, biologists have developed laboratory methods for rapidly determining where each of the 30K genes in the mouse genome is...
Joe D. Warren, Tao Ju, Gregor Eichele, Christina T...
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
We describe algorithms to explore the space of all possible reconciliations between a gene tree and a species tree. We propose an algorithm for generating a random reconciliation, ...
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...