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BIBM
2010
IEEE
222views Bioinformatics» more  BIBM 2010»
13 years 9 months ago
CEO a cloud epistasis computing model in GWAS
The 1000 Genome project has made available a large number of single nucleotide polymorphisms (SNPs) for genome-wide association studies (GWAS). However, the large number of SNPs ha...
Zhengkui Wang, Yue Wang, Kian-Lee Tan, Limsoon Won...
BMCBI
2006
124views more  BMCBI 2006»
13 years 11 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
HPDC
2010
IEEE
13 years 12 months ago
Cloud computing paradigms for pleasingly parallel biomedical applications
Cloud computing offers new approaches for scientific computing that leverage the major commercial hardware and software investment in this area. Closely coupled applications are s...
Thilina Gunarathne, Tak-Lon Wu, Judy Qiu, Geoffrey...
BIOINFORMATICS
2007
123views more  BIOINFORMATICS 2007»
13 years 11 months ago
A comparative genome approach to marker ordering
Motivation: Genome maps are fundamental to the study of an organism and essential in the process of genome sequencing which in turn provides the ultimate map of the genome. The in...
Thomas Faraut, Simon de Givry, Patrick Chabrier, T...
IMSCCS
2006
IEEE
14 years 4 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng