Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
Advances in the development of large scale distributed computing systems such as Grids and Computing Clouds have intensified the need for developing scheduling algorithms capable...
Claris Castillo, George N. Rouskas, Khaled Harfous...
Whether common ancestors of eukaryotes and prokaryotes had introns is one of the oldest unanswered questions in molecular evolution. Recently completed genome sequences have been u...
Alternative splicing is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Finding alternative splicing events experimentally ...
Existing sequence comparison software applications lack automation, abstraction, performance, and flexibility. Users need a new way of studying and applying sequence comparisons i...