Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
We address the problem of using expression data and prior biological knowledge to identify differentially expressed pathways or groups of genes. Following an idea of Ideker et al...
Serban Nacu, Rebecca Critchley-Thorne, Peter Lee, ...
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
This paper discusses different approaches for integrating biological knowledge in gene expression analysis. Indeed we are interested in the fifth step of microarray analysis pro...
We propose a novel semi-supervised clustering method for the task of gene regulatory module discovery. The technique uses data on dna binding as prior knowledge to guide the proces...