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» Clustering Similarity Comparison Using Density Profiles
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BMCBI
2010
122views more  BMCBI 2010»
13 years 7 months ago
An automated framework for understanding structural variations in the binding grooves of MHC class II molecules
Background: MHC/HLA class II molecules are important components of the immune system and play a critical role in processes such as phagocytosis. Understanding peptide recognition ...
Kalidas Yeturu, Tapani Utriainen, Graham J. L. Kem...
BMCBI
2010
155views more  BMCBI 2010»
13 years 4 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 7 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li
CMOT
2004
141views more  CMOT 2004»
13 years 7 months ago
Small Worlds Among Interlocking Directors: Network Structure and Distance in Bipartite Graphs
We describe a methodology to examine bipartite relational data structures as exemplified in networks of corporate interlocking. These structures can be represented as bipartite gr...
Garry Robins, Malcolm Alexander
SDM
2009
SIAM
176views Data Mining» more  SDM 2009»
14 years 4 months ago
Constraint-Based Subspace Clustering.
In high dimensional data, the general performance of traditional clustering algorithms decreases. This is partly because the similarity criterion used by these algorithms becomes ...
Élisa Fromont, Adriana Prado, Céline...